Benefits of CELEBREX ® - Help Relieve Arthritis Pain and Stiffness

Understanding the risks and benefits of NSAIDs is important. All NSAIDs, including CELEBREX, help relieve arthritis pain, but only you and your doctor can decide which one is right for you. An NSAID like CELEBREX might be an arthritis treatment option.

CELEBREX relieves arthritis pain, stiffness, and inflammation. Just one 200-mg dose provides 24-hour relief.

In clinical studies, a lower percentage of patients on CELEBREX reported indigestion, abdominal pain, and nausea versus prescription ibuprofen and naproxen.

If you are taking low-dose aspirin for your heart and need an NSAID pain reliever, CELEBREX can be used because it doesn’t interfere with the effects of low-dose aspirin. Taking low-dose aspirin may not reduce the cardiovascular risk associated with NSAID use. With any NSAID, including CELEBREX, patients also taking aspirin are at an increased risk for stomach bleeding and ulcers. CELEBREX is not a substitute for aspirin in preventing heart attack or stroke.

Based on the available data, the FDA stated that, for certain patients, the benefits of CELEBREX outweigh the risks. But only you and your doctor can make that decision.

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Indications:

CELEBREX is indicated for the relief of the signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and for the management of acute pain in adults.

Important Safety Information:

Like all prescription NSAIDs, CELEBREX may increase the chance of heart attack or stroke that can lead to death. This chance increases if you have heart disease or risk factors for it, such as high blood pressure or when NSAIDs are taken for long periods.

CELEBREX should not be used right before or after certain heart surgeries.

Serious skin reactions, or stomach and intestine problems such as bleeding and ulcers, can occur without warning and may cause death. Patients taking aspirin and the elderly are at increased risk for stomach bleeding and ulcers.

Tell your doctor if you have:
* A history of ulcers or bleeding in the stomach or intestines
* High blood pressure or heart failure
* Kidney or liver problems

CELEBREX should not be taken in late pregnancy.

Do not take CELEBREX if you've had an asthma attack, hives, or other allergic reactions to aspirin, any other NSAID medicine, or certain drugs called sulfonamides.

Life threatening allergic reactions can occur with CELEBREX. Get help right away if you've had swelling of the face or throat or trouble breathing.

Prescription CELEBREX should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.

For more information about CELEBREX and other NSAIDs, please see the Medication Guide.
For further information on CELEBREX, please see the full Prescribing Information.

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This Web site is intended for residents of the United States only. The products discussed herein may have different product labeling in different countries.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. Decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.

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Last Updated: August 23, 2010